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Meriva-500 is a unique, patented curcumin product. People throughout Asia have benefited from the healthful effects of curcumin for centuries. Curcumin is the orange pigment in turmeric (the primary ingredient in curry), and is a potent antioxidant that offers numerous health benefits, including supporting joint health and hepatic, GI, and cardiovascular function, by helping to maintain the bodys normal inflammatory response.*
Whether taken as a supplement or from food, curcumin is generally poorly absorbed into the bloodstream. In conjunction with Indena S.p.A., the worldwide experts in botanical extract technology, we have uncovered the key to curcumin absorption – phytosome technology. Meriva curcumin phytosome is a unique curcumin extract that is significantly better absorbed than other curcumin extracts.*
Phytosomes are plant extracts bound to phosphatidylcholine (PC), an essential component of human cells. Our bodies can make PC, but we can also get it from food or supplements. When taken orally, PC is very well absorbed. The scientists at Indena found a way to attach a curcumin extract to PC for superior absorption, resulting in Meriva. When you take Meriva your body absorbs the PC and the attached curcumin, resulting in more curcumin reaching the cells that can benefit from it.*
A 2007 single-dose pharmacokinetic animal study demonstrated Merivas superior bioavailability, compared to ordinary curcumin.* The results demonstrated a >20-fold increase in absorption of curcumin from Meriva versus a standard curcumin preparation.* In addition, a 2010 three-month clinical trial demonstrated 1,000 mg of Meriva-SR per day helped maintain healthy C-reactive protein levels and promoted healthy joint comfort and mobility.* Furthermore, a 2010 randomized, single-blind, crossover human study revealed total curcuminoid bioavailability, as evaluated by the plasma area under the curve (AUC), to be 29-fold higher for Meriva than for the conventional standardized curcumin extract.*
Several studies have illustrated curcumins hepatoprotective effects, leading researchers to suggest its use in protecting the liver from exogenous insults from environmental toxins.* Curcumin also has the capacity to increase both the flow and solubility of bile.* Curcumins hepatoprotective effects are due in part to direct free-radical scavenging; but curcumin also enhances the bodys natural antioxidant system, which increases glutathione levels, thereby aiding in hepatic detoxification and inhibiting nitrosamine formation.*
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
Meriva-500 contains curcumin phytosome – a plant extract complexed with phosphatidylcholine, which is derived from soy. Phosphatidylcholine contains no soy protein. There are no other soy-based ingredients in Meriva-500.
This product does not contain wheat, gluten, corn, yeast, egg, dairy products, or artificial colors, artificial sweeteners, or artificial flavors. This product also does not contain lactose, palmitic acid, magnesium stearate, or stearic acid.
If pregnant, consult your health-care practitioner before using this product.
Curcumin has been shown to reduce the therapeutic efficacy of cyclophosphamide (Cytoxan) in animal studies. In vitro research revealed that curcumin decreased camptothecin-induced death of cultured breast cancer cells. Curcumin might also interfere with the absorption and efficacy of the chemotherapy drug irinotecan, used to treat colon cancer. The concurrent use of curcumin with these agents should be avoided.