This product contains BioCell Collagen, a patented, hydrolyzed and denatured low molecular weight collagen. In addition to collagen, BioCell Collagen provides the combined benefits of hyaluronic acid (HA), depolymerized low molecular weight chondroitin sulfate, glucosamine sulfate, and amino acids including lysine, proline and hydroxyproline. These compounds promote cartilage synthesis and enhance synovial fluid, supporting the composition, integrity and motility of joints. A double blind placebo-controlled study involving 16 individuals supplementing with BioCell Collagen for 8 weeks, indicated statistically significant support for joint function and comfort. In a peak absorption study, serum levels of HA increased gradually and with statistical significance after BioCell Collagen supplementation, emphasizing the potential for this compound to provide important connective tissue support. The components of collagen also support the elasticity and firmness of skin. Furthermore, HA attracts water, promoting hydration and moisture retention within the dermal matrix. Case reports have suggested that BioCell Collagen may help rejuvenate skin and modulate the appearance of fine lines and wrinkles.
Pure Encapsulations recommends 2-4 capsules per day, in divided doses, with 8–10 oz water, with meals.
Rare side effects of glucosamine and chondroitin found in hydrolyzed type II collagen include nausea, heartburn, diarrhea and constipation, drowsiness, skin reactions, or headache. If pregnant or lactating, consult your physician before taking this product.